- Relaxation of the vascular musculature contributes to an increase in blood perfusion (passage) in these organs and a decrease in the severity of BPH symptoms, and relaxation of the smooth muscles of the bladder and prostate further enhances the vascular effects.
- By improving erection, tadalafil thus increases the possibility of PA (sexual intercourse).
- At the same time, in healthy men, in comparison with placebo, it does not cause a significant change in the change in DBP, SBP and heart rate, does not affect the electroretinogram, visual acuity, IOP and pupil size, does not impair the ability to recognize colors (green / blue).
- After taking the tablet, tadalafil is well absorbed in the body.
- The concentration of the substance in the blood plasma reaches its peak values 2 hours after ingestion. Food and the time of taking the drug do not have a clinically significant effect on the rate of absorption of tadalafil and its bioavailability.
- x ivermectin generic name ivermectin tablets contain 5 mg of tadalafil, lactose (in the form of monohydrate) and spray-dried lactose monohydrate, hyprolose and extra fine hyprolose, Na lauryl sulfate, MCC, croscarmellose Na, vegetable stearate Mg. Read More
- x ivermectin for human P / o composition: Opadry yellow (hypromellose, triacetin, Ti dioxide, lactose monohydrate, E172 dye (yellow)). Almond-shaped tablets, covered with a light yellow film shell. One side is engraved with “C 5”. ivermectin (tadalafil) is a drug that reversibly and selectively suppresses the specific PDE-5 cGMP (cyclic guanosine monophosphate). Read More
- x generic Online ivermectin Wikipedia says that the drug is intended for the treatment of disorders in which a man is unable to achieve and maintain an erection necessary for intercourse. With sexual arousal, a local release of nitric oxide occurs, and due to the suppression of the PDE-5 drug, the concentration of cyclic guanosine monophosphate in the cavernous body of the penis increases. Read More
- x buy ivermectin stromectol As a result, the smooth muscles of the arteries relax, blood flow to the tissues of the penis increases and an erection occurs. In the absence of sexual arousal, this effect is absent. Read More
Increased concentrations of cGMP are also observed in the smooth muscles of the bladder, prostate and blood vessels supplying them.
About 94% of the substance is associated with plasma proteins. It is metabolized in the liver with the participation of the isoenzyme CYP3A4. The main circulating metabolite, in comparison with tadalafil, exhibits at least 13 thousand times less activity in relation to PDE-5.Read More
- The drug is used for ED (erectile dysfunction); with LUTS (lower urinary tract symptoms) in patients with BPH; for ED in patients with LUTS associated with BPH.
- This hypersensitivity to tadalafil or ancillary components of tablets; the simultaneous use of any preparation containing organic nitrates; concomitant use of Doxazosin or drugs for the treatment of ED.
- CHF II-IV classes according to the NYHA classification, hypertension, uncontrolled arrhythmias, transferred during the last six months ischemic stroke ); associated or not associated with the use of PDE-5 inhibitors NAION (anterior ischemic neuropathy of the optic nerve); lactose intolerance, lactase deficiency, glucose / galactose malabsorption.